Three-layer collagen-based vascular graft designed for low-flow peripheral vascular reconstructions

A collagen/vascular smooth muscle cells (SMCs) incorporating elastic scaffold for tissue-engineered vascular graft

Statement of Purpose: This study was focused on a collagen/cell mixture seeding method to improve the adhesion and proliferation of vascular smooth muscle cells (SMCs) in tubular porous scaffolds for vascular grafts application. Recently, poly(L-lactide-co-εcaprolactone) (PLCL) copolymers have been applied as a biomaterial for vascular graft due to the high elastic property. We previously repor...

Flow-augmentation device for peripheral vascular Doppler US.

To augment venous blood flow at Doppler ultrasonography (US) of the extremities, a device comprising a blood pressure cuff connected to an external reservoir was tested. Constant and easily controlled pressure was delivered with each compression by the same operator performing US. In 10 patients (four men and six women, aged 54-86 years), discomfort was reduced compared with discomfort during m...

Low-flow motion in the vascular ocean.

Vascular graft infections.

Vascular procedures are rarely complicated by infection, but if prosthetic vascular graft infection (PVGI) occurs, morbidity and mortality are high. Several patient-related, surgery-related and postoperative risk factors are reported, but they are not well validated. PVGI is due to bacterial colonisation of the wound and the underlying prosthetic graft, generally as a result of direct contamina...

Flow patterns through vascular graft models with and without cuffs

The shape of a bypass graft plays an important role on its efficacy. Here, we investigated flow through two vascular graft designs-with and without cuff at the anastomosis. We conducted Digital Particle Image Velocimetry (DPIV) measurements to obtain the flow field information through these vascular grafts. Two pulsatile flow waveforms corresponding to cardiac cycles during the rest and the exc...